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istradefylline will enhance the stage or impact of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.dabrafenib will lower the level or influence of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of abemaciclib with robust CYP3A4 inducers le